Quantum Regenerative and Biomedical Engineering Team

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Aiming for Innovation in Regenerative Medicine with Quantum Technology

By applying quantum technologies such as nano quantum sensors to regenerative medicine and engineering, we are working to create technologies for measuring and diagnosing the cellular state of stem cells and regenerative cells in the in vivo environment, tissues, and organs, and for quality control prior to transplantation. Our goal is to contribute to the fields of regenerative medicine and embryology while deepening our understanding of the cellular state of stem cells and regenerative cells both in vivo and in vitro.

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OVERVIEW

RESEARCH

Visualization with Quantum Technology!
New Possibilities in Regenerative and Biomedical Engineering

By applying quantum technologies such as nano quantum sensors to regenerative medicine and engineering, we will work to create technologies for measuring and diagnosing (quality control) the cellular state of stem cells and regenerative cells in the in vivo environment, tissues, and organs, not only before transplantation but also after transplantation.

Development of Nano Quantum sensor and its Application to In Vivo Observation and Diagnosis of Stem Cells and Regenerative Cells
Development of Near-Infrared Nano Quantum Sensor and its Application to In Vivo Deep Imaging Diagnosis and Therapy
Nano Quantum Sensor Live Imaging of Cell Activity in the Brain Applied to Regenerative Medicine for Neurological Disease
Creation of Cell Measurement and Manipulation Technology by Fusion of Nano Quantum Sensor and Microfluidics and Quantum Life Science Application

NEWS

01 April 2025

The paper by Project Director Yukawa, Director Baba, Deputy Director Kono, and others has been selected as the journal cover art for April 2025. Congratulation.

29 March 2025

Team Leader Yukawa delivered an invited symposium lecture at the 145th Annual Meeting of the Pharmaceutical Society of Japan, Fukuoka, Japan.

24 March 2025

Team Leader Yukawa gave an invited lecture at the 3rd Q-BReD Collaboration Seminar hosted by Tokai National Organization Quantum Frontier Industry Creation Center.

19 March 2025

Graduate student Hatakeyama gave a poster presentation and a short talk at APPW2025 (Chiba, Japan), co-authored with Senior Researcher Agetsuma.

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PUBLICATION

  • †Takahashi T., †Zhou Y., †Tsutsumi M., †Ito C., Hatakeyama A., Ishii H., Saitoh A., Yukawa H., Nabekura J., Nemoto T., *Otomo Kohei., *Matsuhisa N., *Agetsuma M. In vivo deep-brain microscopy at submicrometer resolution with refractive index-matched prism interfaces, bioRxiv 2025.

  • Jiang C., Sakai T., Akiyoshi K., Kameyama T., Kumagai J., Yamada S., Yukawa H., Baba Y., Uematsu T., *Torimoto T. Tuning Photoluminescence and Magnetic Properties of Ag–Ga–S and Zn–Ag–Ga–S Quantum Dots via Mn²⁺ Doping, Electrochemistry 2025; in press.

  • O’Neill S. J.K., Ashizawa M., McLean A.M., Serrano R. R.-M., Shimura T., Agetsuma M., Tsutsumi M., Nemoto T., Parmenter C.D.J., McCune J.A., Malliaras G.G., Matsuhisa N., Scherman O.A. Supramolecular conductive hydrogels with homogeneous ionic and electronic transport, Advanced Materials 2025; 2415687.

  • Rismaningsih N., Kubo J., SotoM., Akiyoshi K., Kameyama T., Yamamoto T., *Yukawa H., Baba Y., *Torimoto T. Near-Infrared Photoluminescence of Ag8GeS6 Quantum Dots through Compositional Fine-tuning and ZnS Coating for In Vivo Bioimaging, Small 2025; 2411142.

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